Zimmerman – Publications – Full List

Zimmerman – Publications – Full List


  • The Flip-Flop Diffusion Mechanism across Lipids in a Hybrid Bilayer Membrane

    Barile C. J.; Tse E. C. M.; Li Y.; Gewargis J. P.; Kirchschlager N. A.; Zimmerman S. C.; Gewirth A. A

    Biophysical Journal 2016, 110, 2451-62

    DOI: http://dx.doi.org/10.1016/j.bpj.2016.04.041

  • Chemical Control over Cellular Uptake of Organic Nanoparticles by Fine Tuning Surface Functional Groups

    Bai Yugang; Xing Hang; Feng Xinxin; Hwang Kevin; Lee Jennifer M; Phang Xin Yi; Lu Yi; Zimmerman Steven C;

    Xing Hang; Lu Yi

    ACS Nano, 2015, 9, 10227–10236

    DOI: 10.1021/acsnano.5b03909

  • A Highly Efficient Single-Chain Metal–Organic Nanoparticle Catalyst for Alkyne–Azide “Click” Reactions in Water and in Cells

    Bai, Y.; Feng, X.; Xing, H.; Xu, Y.; Kim, B. K.; Baig, N.; Zhou, T.; Gewirth, A. A.; Lu, Y.; Oldfield, E. Zimmerman, S. C.

    J. Am. Chem. Soc., 2016, 138, 11077–11080

    DOI: 10.1021/jacs.6b04477

  • A Potent Inhibitor of Protein Sequestration by Expanded Triplet (CUG) Repeats that Shows Phenotypic Improvements in a Drosophila Model of Myotonic Dystrophy

    Luu, L. M., Nguyen, L., Peng, S., Lee, J., Lee, H. Y., Wong, C.-H., Hergenrother, P. J., Chan, H. Y. E. and Zimmerman, S. C. 

    ChemMedChem 2016, 11, 1428–1435 

    DOI: 10.1002/cmdc.201600081

  • Crosslinked dendronized polyols as a general approach to brighter and more stable fluorophores

    Li, Y.; Bai, Y.; Zheng, N.; Liu, Y.; Vincil, G. A.; Pedretti, B. J.; Cheng, J.; Zimmerman, S. C. 

    Chem. Commun., 201652, 3781-3784

    DOI: 10.1039/C5CC09430E

  • A journey in bioinspired supramolecular chemistry: from molecular tweezers to small molecules that target myotonic dystrophy

    Zimmerman, S. C. 

    Beilstein J. Org. Chem. 2016, 12, 125–138



  • Hydrophilic packaging of iron oxide nanoclusters for highly sensitive imaging

    Smith, C. E.; Ernenwein, D.; Shkumatov, A.; Clay, N. E.; Lee, J.; Melhem, M.; Misra, S.; Zimmerman, S. C.; Kong, H. 

    Biomaterials 2015, 69, 184–190


  • Rationally Designed Small Molecules That Target Both the DNA and RNA Causing Myotonic Dystrophy Type 1

    Nguyen, L., Luu, L. M., Peng, S., Serrano, J. F., Chan, H. Y. E., Zimmerman, S. C

    J. Am. Chem. Soc., 2015, 137 (44), pp 14180–14189

    DOI: 10.1021/jacs.5b09266

  • Photo-responsive Molecular Switch for Regulating Trans-membrane Proton Transfer Kinetics

    Ying Li, Edmund C. M. Tse, Christopher J. Barile, Andrew A. Gewirth, and Steven C. Zimmerman

    Journal of the American Chemical Society Just Accepted Manuscript

    DOI: 10.1021/jacs.5b10016

  • A double supramolecular crosslinked polymer gel exhibiting macroscale expansion and contraction behavior and multistimuli responsiveness

    Xiaofan Ji, Kecheng Jie, Steven C. Zimmerman and Feihe Huang  Polym. Chem., 2015,6, 1912-1917

    DOI: 10.1039/C4PY01715C

  • Anion Transport through Lipids in a Hybrid Bilayer Membrane

    Tse, E. C. M., Barile, C. J., Gewargis, J. P., Li, Y., Zimmerman, S. C., Gewirth, A. A.

    Anal. Chem. 2015 87, 2403-2409

    DOI: 10.1021/ac5043544

  • Small Molecules that Target the Toxic RNA in Myotonic Dystrophy Type 2

    Lien Nguyen, JuYeon Lee, and Steven C. Zimmerman ChemMedChem 2014, 9, 2455-62 DOI: 10.1002/cmdc.201402095

  • Practical Synthesis of Water-Soluble Organic Nanoparticles with a Single Reactive Group and a Functional Carrier Scaffold

    Yugang Bai, Hang Xing, N. Gabriel Lemcoff, Yi Lu, and Steven C. Zimmerman Chem. Sci. 2014, 5, 2862-2868. DOI: 10.1039/C4SC00700J

  • Targeting Toxic RNAs that Cause Myotonic Dystrophy Type 1 (DM1) with a Bisamidinium Inhibitor

    Chun-Ho Wong, Lien Nguyen, Jessie Peh, Long M. Luu, Jeannette S. Sanchez, Stacie L. Richardson, Tiziano Tuccinardi, Tsoi Ho, Edwin H. Y. Chan, Wood-Yee Chan, Anne M. Baranger, Paul J. Hergenrother, and Steven C. Zimmerman J. Am. Chem. Soc. 2014, 136, 6355–6361. DOI: 10.1021/ja5012146

  • Isaiah Shavitt: Computational Chemistry Pioneer

    Steven C. Zimmerman and Russell M. Pitzer Theor. Chem. Acct. 2014113, (1488), 1-7. DOI:10.1007/s00214-014-1488-3

  • Proton Switch for Modulating Oxygen Reduction by a Copper Electrocatalyst Embedded in a Hybrid Bilayer Membrane

    Christopher J. Barile, Edmund C. M. Tse, Ying Li, Thomas B. Sobyra, Steven C. Zimmerman, Ali Hosseini, and Andrew A. Gewirth Nature Mater. 201413, 619–623. DOI: 10.1038/nmat3974

  • Developing Bivalent Ligands to Target CUG Triplet Repeats as the Causative Agent of Myotonic Dystrophy Type 1

    Amin Haghighat Jahromi, Yuan Fu, Lien Nguyen, Kali A. Miller, Anne M. Baranger, and Steven C. Zimmerman J. Med. Chem. 2013, 56(23), 9471–9481. DOI: 10.1021/jm400794z

  • A Polymeric Fastener to Localize Gadolinium on a Liposome Surface for Enhanced Magnetic Resonance Imaging

    Cartney E. Smith , Artem Shkumatov , Sarah G. Withers , James F. Glockner , Sanjay Misra , Edward J. Roy , Chun-Ho Wong , Steven C. Zimmerman , and Hyunjoon Kong ACS Nano 2013, 7, 9599-9610. DOI: 10.1021/nn4026228

  • Hydrogen Bonding Modules for Use in Supramolecular Polymers

    Si Kyung Yang and Steven C. Zimmerman, Isr. J. Chem. 2013, 53, 511-520. Cover Article. DOI: 10.1002/ijch.201300045

  • Supramolecular Chemistry for Biology, Materials and Medicine

    Alanna Schepartz and Steven C. Zimmerman Isr. J. Chem. 2013, 53, 495-496. DOI: 10.1002/ijch.201310007.

  • Ring-fused BODIPY as a Single-Molecule Optical Probe with Suppressed Blinking and Long Lifetime

    Si Kyung Yang, Xinghua Shi, Taekjip Ha, and Steven C. Zimmerman Nature Chem. 2013, 5, 692-697. DOI:10.1038/nchem.1706.

  • Single molecule study of the CUG Repeat⋅MBNL1 Interaction and its Inhibition by Small Molecule

    Amin Haghighat Jahromi, Masayoshi Honda, Steven C. Zimmerman, and Maria Spies Nucl. Acids Res. 2013, 41 (13), 6687-6697. DOI: 10.1093/nar/gkt330. Cover Article.

  • Quadruply Hydrogen Bonding Modules as Highly Selective Nanoscale Adhesive Agents

    Yagang Zhang, Cyrus A. Anderson, and Steven C. Zimmerman Org. Lett. 2013, 15, 3506–3509. DOI: 10.1021/ol401035t.

  • Leukocyte-Mimicking Stem Cell Delivery via In situ Coating of Cells with a Bioactive Polyglycerol

    John J. Schmidt, Jae Hyun Jeong, Richie Kohman, Andrew Zill, Ross DeVolder, Steven C. Zimmerman, and Hyunjoon Kong  J. Am. Chem. Soc. 2013, 135, 8770-8773. DOI: 10.1021/ja4005283. Cover Article.

  • High-Affinity DNA Base Analogs as Supramolecular, Nanoscale Promoters of Macroscopic Adhesion9

    Cyrus A. Anderson, Amanda R. Jones, Ellen M. Briggs, Eric J. Novitsky, Darrell W. Kuykendall, Nancy R. Sottos, and Steven C. Zimmerman J. Am. Chem. Soc. 2013, 135, 7288–7295.  DOI: 10.1021/ja4005283

  • A Novel CUGexp·MBNL1 Inhibitor with Therapeutic Potential for Myotonic Dystrophy Type 1

    Amin Haghighat Jahromi, Lien Nguyen, Yuan Fu, Kali Miller, Anne M. Baranger, and Steven C. Zimmerman ACS Chem. Biol. 2013, 8, 1037-1043. DOI: 10.1021/cb400046u. Cover Article.

  • Orthogonality in Organic, Polymer, and Supramolecular Chemistry: from Merrifield to Click Chemistry

    Chun-Ho Wong and Steven C. Zimmerman Chem. Commun. 2013, 49, 1679-1695. DOI: 10.1039/c2cc37316e. Cover Article.

  • Azobenzene Dye Coupled Quadruple Hydrogen Bonding Modules as Colorimetric Indicators for Supramolecular Interactions

    Yagang Zhang and Steven C. Zimmerman Beilstein J. Org. Chem. 2012, 8, 486–495. DOI: 10.3762/bjoc.8.55.

  • Investigating the Binding Mode of an Inhibitor of the MBNL1⋅RNA Complex in Myotonic Dystrophy Type 1 (DM1) Leads to the Unexpected Discovery of a DNA-Selective Binder

    Chun-Ho Wong, Stacie L. Richardson, Yen-Jun Ho, Alex M. H. Lucas, Tiziano Tuccinardi, Anne M. Baranger, and Steven C. Zimmerman ChemBioChem 2012, 13, 2505-2509. DOI: 10.1002/cbic.201200602.

  • Polyglycerol-Dendronized Perylenediimides as Stable, Water-soluble Fluorophores

    Si Kyung Yang and Steven C. Zimmerman Adv. Funct. Mater. 2012, 22, 3023-3028. DOI: 10.1002/adfm.201200004.

  • Calix[8]arene Functionalized Polyglycerol Nanogels for Encapsulation and Stabilization of Fluorescent Dyes

    Dirk Steinhilber, Florian Paulus, Andrew T. Zill, Steven C. Zimmerman and Rainer Haag MRS Proc. 2012, 1403, 185-193. DOI: 10.1557/opl.2012.419.

  • Synthesis and Properties of Fluorescent Dyes Conjugated to Hyperbranched Polyglycerols

    Andrew T. Zill, Kai Licha, Rainer Haag, Steven C. Zimmerman New J. Chem. 2012, 36, 419-427. DOI: 10.1039/C1NJ20476A.

  • Top-Down Synthesis of Versatile Polyaspartamide Linkers for Single-Step Protein Conjugation to Materials

    Chaenyung Cha, Jae Hyun Jeong, Xin Tang, Andrew T. Zill, Y. S. Prakash, Steven C. Zimmerman, Taher A. Saif, Hyun-Joon Kong Bioconjug. Chem. 2011, 22, 2377-2382.  DOI: 10.1021/bc200339s.

  • Synthesis of a Redox-Responsive Quadruple Hydrogen-Bonding Unit for Applications in Supramolecular Chemistry

    Ying Li, Taiho Park, J. Kwansima Quansah, Steven C. Zimmerman J. Am. Chem. Soc. 2011, 133, 17118–17121.

  • Selective Inhibition of MBNL1–CCUG Interaction by Small Molecules Toward Potential Therapeutic Agents for Myotonic Dystrophy Type 2 (DM2)

    Chun-Ho Wong, Yuan Fu, Sreenivasa Rao Ramisetty, Anne M. Baranger, Steven C. Zimmerman Nucleic Acids Res. 2011, 39, 8881–8890.

  • Monovalent and Clickable, Uncharged Water-Soluble Perylenedimide-Cored Dendrimers for Target-Specific, Fluorescent Biolabeling

    Si Kyung Yang, Xinghua Shi, Seongjin Park, Sultan Doganay, Taekjip Ha, Steven C. Zimmerman J. Am. Chem. Soc. 2011, 133, 9964–9967.

  • Clickable Polyglycerol Hyperbranched Polymers and Their Application to Gold Nanoparticles and Acid-Labile Nanocarriers

    Andrew Zill, Alexandra L. Rutz, Richie E. Kohman, Alaaldin M. Alkilany, Catherine J. Murphy, Hyunjoon Kong, Steven C. Zimmerman Chem. Commun. 2011, 47, 1279–1281.

  • Direct, Electrocatalytic Oxygen Reduction by Laccase on Anthracene-2-methanethiol-Modified Gold

    Matthew S. Thorum, Cyrus A. Anderson, Jeremy J. Hatch, Andrew S. Campbell, Nicholas M. Marshall, Steven C. Zimmerman, Yi Lu, and Andrew A. Gewirth J. Phys. Chem. Lett. 2010, 1, 2251–2254.

  • Room Temperature, Copper-Catalyzed Amination of Bromonaphthyridines with Aqueous Ammonia

    Cyrus A. Anderson, Phillip G. Taylor, Mary A. Zeller, Steven C. Zimmerman J. Org. Chem. 2010, 75, 4848–4851.

  • Tuning Hydrogel Properties and Function using Substituent Effects

    Richie E. Kohman, Chaenyung Cha, Steven C. Zimmerman, Hyunjoon Kong Soft Matter 2010, 6, 2150–2152.

  • A simple ligand that selectively targets CUG trinucleotide repeats and inhibits MBNL protein binding

    Jonathan F. Arambula, Sreenivasa Rao Ramisetty, Anne M. Baranger, and Steven C. Zimmerman Proc. Natl. Acad. Sci. U.S.A. 2009, 106, 16068–16073.

  • Photoresponsive Crosslinked Hyperbranched Polyglycerols as Smart Nanocarriers for Guest Binding and Controlled Release

    Ewelina Burakowska, Steven C. Zimmerman, and Rainer Haag Small 2009, 5, 2199–2204.

  • A route to water-soluble molecularly templated nanoparticles using click chemistry and alkyne-functionalized hyper-branched polyglycerol

    Andrew T. Zill and Steven C. Zimmerman Isr. J. Chem. 2009, 49, 71–78.

  • Prebiotic Selection of the AU Base-Pair? A Physical Organic Approach to Understanding AT Base-Pair Stability Indicates Special Stability

    Jordan R. Quinn, Steven C. Zimmerman, Janet E. Del Bene, and Isaiah Shavitt in Chemical Evolution II: From Origins of Life to Modern Society, Lori Zaikowski and Jon M Friedrich, Editors, ACS Books,2009.

  • Cross-linked hyperbranched polyglycerols as hosts for selective binding of guest molecules

    Ewelina Burakowska, Jordan R. Quinn, Steven C. Zimmerman, and Rainer Haag J. Am. Chem. Soc. 2009, 131, 10574–10580.

  • Modeling the equilibria of complex supramolecular systems

    Eric M. Todd and Steven C. Zimmerman J. Chem. Educ. 2009, 86, 638–643.

  • Switching the selectivity of a polyglycerol dendrimer monomolecularly imprinted with D-(–)-fructose

    Akihito Hashidzume and Steven C. Zimmerman Tetrahedron Lett.2009, 50, 2204–2207.

  • Degradable dendrimers divergently synthesized via click chemistry

    Richie E. Kohman and Steven C. Zimmerman Chem. Commun. 2009, 794–796.

  • Molecular recognition of a thymine bulge by a high affinity, deazaguanine-based hydrogen-bonding ligand

    Hugo C. Ong, Jonathan F. Arambula, Sreenivasa Rao Ramisetty, Anne M. Baranger, and Steven C. Zimmerman Chem. Commun. 2009, 668–670.

  • Hydrogen-Bonded DeUG•DAN Heterocomplex: Structure and Stability and a Scalable Synthesis of DeUG with Reactive Functionality

    Darrell W. Kuykendall, Cyrus A. Anderson, and Steven C. Zimmerman Org. Lett. 2009, 11, 61–64.

  • Synthesis of polyglycerol, porphyrin-cored dendrimers using click chemistry

    Stephanie L. Elmer, Sonny Man, and Steven C. Zimmerman Eur. J. Org. Chem. 2008, 3845–3851.

  • Bis-ureidodeazapterin (Bis-DeAP) as a general route to supramolecular star polymers

    Eric M. Todd and Steven C. Zimmerman Tetrahedron 2008, 64, 8558–8570.

  • Cross-linked glycerol dendrimers and hyperbranched polymers as ionophoric, organic nanoparticles soluble in water and organic solvents

    Steven C. Zimmerman, Jordan R. Quinn, Ewelina Burakowska, and Rainer Haag Angew. Chem. Int. Ed. 2007, 46, 8164–8167.

  • Supramolecular Star Polymers. Increased Molecular Weight with Decreased Polydispersity through Self-Assembly

    Eric M. Todd and Steven C. Zimmerman J. Am. Chem. Soc. 2007, 129, 14534–14535.

  • Exploring the Reversibility of the Ring-Closing Metathesis Mediated Cross-linking of Dendrimers

    Stephanie L. Elmer, N. Gabriel Lemcoff, and Steven C. Zimmerman Macromolecules 2007, 40, 8114–8118.

  • A Very Versatile Nanocapsule

    Darrell Kuykendall and Steven C. Zimmerman Nat. Nanotechnol. 2007, 2, 201–202.

  • Supramolecular polymers formed by intermolecular interaction of hydrogen bonding

    Taiho Park, Steven C. Zimmerman, Hugo C. Ong, Eric M. Todd, Darrell W. Kuykendall, Kwansima Quansah PMSE Preprints 2007, 96, 138–139.

  • Does the A•T or G•C Base-Pair Possess Enhanced Stability? Quantifying the Effects of CH•••O Interactions and Secondary Interactions on Base-Pair Stability Using a Phenomenological Analysis and Ab Initio Calculations

    Jordan R. Quinn, Steven C. Zimmerman, Janet E. Del Bene, and Isaiah Shavitt  J. Am. Chem. Soc. 2007, 128, 934–941.

  • Interplay of Fidelity, Binding Strength, and Structure in Supramolecular Polymers

    Taiho Park and Steven C. Zimmerman J. Am. Chem. Soc. 2006, 128, 14236–14237.

  • A Supramolecular Multi-Block Copolymer with a High Propensity for Alternation

    Taiho Park and Steven C. Zimmerman J. Am. Chem. Soc. 2006, 128, 13986–13987.

  • Formation of a Miscible Supramolecular Polymer Blend through Self-Assembly Mediated by a Quadruply Hydrogen-Bonded Heterocomplex

    Taiho Park and Steven C. Zimmerman  J. Am. Chem. Soc. 2006, 128, 11582–11590.

  • Higher Affinity Quadruply Hydrogen-Bonded Complexation with 7-Deaza-guanine Urea (DeUG)

    Hugo Ong and Steven C. Zimmerman Org. Lett. 2006, 8, 1589–1592.

  • Synthesis and Characterization of an Electroactive Surface that Releases γ-Aminobutyric Acid (GABA)

    Chun Yan, Wakana Matsuda, David R. Pepperberg, and Steven C. Zimmerman, Deborah E. Leckbandtive  J Colloid Interfac. Sci. 2006, 296, 165–177.

  • A Quadruply Hydrogen Bonded Heterocomplex Displaying High Fidelity Recognition

    Taiho Park, Shoji Nakashima, Eric J. Todd, and Steven C. Zimmerman  J. Am. Chem. Soc.2005, 125, 18133-18142.

  • Synthesis of a Soluble Ureido-Naphthyridine Oligomer that Self-Associates via Eight Contiguous Hydrogen Bonds

    Michael F. Mayer, Shoji Nakashima, and Steven C. Zimmerman Org. Lett. 2005, 7, 3005-3008.

  • Structure-Property Relationships in Supramolecular Polymer Chemistry

    Steven C. Zimmerman and Taiho Park Polym. Prepr., (Am. Chem. Soc. Div. Polym. Chem.), 2005, 42, 1159-1160.

  • Fidelity in the Supramolecular Assembly of Triply and Quadruply Hydrogen Bonded Complexes

    Eric M. Todd, Jordan R. Quinn, Taiho Park, and Steven C. Zimmerman Isr. J. Chem. 2005, 45, 381-389.

  • Linear Supramolecular Polymers and Networks

    Perry S. Corbin and Steven C. Zimmerman in Supramolecular Polymers, Ed. A. Cifferi; CRC Press: New York; 2005.

  • Structure-Function Studies on s Synthetic Guanosine Receptor that Simultaneously Binds Watson_Crick and Hoogsteen Sties

    Jordan R. Quinn, Steven C. Zimmerman J. Org. Chem. 2005, 70(1), 7459-7469.

  • Preparation of 2,7-Diamino-1,8-naphthyridine, A Useful Building Block for Supramolecular Chemistry

    Taiho Park, Michael F. Mayer, Shoji Nakashima, Steven C. Zimmerman in 2005, 70(1), 7459-7469   Synlett 2005, 1435-1436.

  • A Highly Stable Quadruply Hydrogen Bonded Heterocomplex Useful for Supramolecular Polymer Blends

    Taiho Park, Steven C. Zimmerman, Shoji Nakashima J. Am. Chem. Soc. 2005, 127, 6520-6521.